Polyvinylpyrrolidone Excipients for Pharmaceuticals: Povidone
Product Name:Copvodione
Chemical Description:Vinylpyrrolidone with Vinyl Acetate Copolymer,PVP/VA 64 Powder
INCI/CTFA:VP/VA Copolymer
Pharmacopeia Name:Copovidone(Copovidonum)
CAS NO.:25086-89-9
Formula structure:
Properties: White or creamy white,free-flowing power with characteristic smell,hygroscopic.Good solubility in water,alcohol and other organic solvents.
Applications:In view of its excellent adhesiveness ,film hard and other properties,Copovidone mainly used as water-soluble binder and dry binder in wet/direct granulation processes,also it can be used as film forming materials.
Specifications:
Appearance |
White to creamy white,free-flowing powder |
K Value(Labled K value at 30) |
27-32.4 |
Aldehyde |
500 ppm max. |
Peroxide |
400 ppm max. |
Hydrazine |
1 ppm max. |
Monomers(Residue VP+Residue VA) |
0.1% max. |
Impurity A(2-Pyrrolidone) |
0.5% max. |
Heavy Metals |
20 ppm max. |
Moisture |
5.0% max. |
Sulphated Ash |
0.1% max. |
VA content |
35.3-42% max. |
Nitrogen |
7.0-8.0 % |